| Product name | MY18B Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human MY18B protein at amino acid sequence of 1680-1760 |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC,IF |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Unconventional myosin-XVIIIb |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 282kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | MYO18B (Myosin XVIIIB) is a Protein Coding gene. Diseases associated with MYO18B include Klippel-Feil Syndrome 4, Autosomal Recessive, With Myopathy And Facial Dysmorphism and Klippel-Feil Syndrome 4. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. The protein encoded by MYO18B may regulate muscle-specific genes when in the nucleus and may influence intracellular trafficking when in the cytoplasm. The encoded protein functions as a homodimer and may interact with F actin. Mutations in MYO18B are associated with lung cancer. |
| Gene ID | 84700 |
| Alternative | Unconventional myosin-XVIIIb |
| Others | The antibody detects endogenous levels of MY18B protein |
| Accession | Q8IUG5 |
| Observed Band(KD) | 282 |
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