| Product name | MRGRD Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human MRGRD protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Mas-related G-protein coupled receptor member D; Beta-alanine receptor; G-protein coupled receptor TGR7 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 35kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | MRGPRD (MAS Related GPR Family Member D) is a Protein Coding gene. Among its related pathways are ACE Inhibitor Pathway, Pharmacodynamics. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). |
| Gene ID | 116512 |
| Alternative | Mas-related G-protein coupled receptor member D; Beta-alanine receptor; G-protein coupled receptor TGR7 |
| Others | The antibody detects endogenous levels of MRGRD protein |
| Accession | Q8TDS7 |
| Observed Band(KD) | 35 |
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