| Product name | Mouse IL-38 Protein, His tag (Animal-Free) |
| Sequence | Amino acid sequence derived from mouse IL-38 (Met 1-Arg 152). |
| Protein length | 17-25 kDa |
| Preparation method | E. coli |
| Purity | >98% as determined by SDS-PAGE. |
| Alternative | interleukin 1 family, member 10, IL1F10 |
| Features & Benefits | Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method. |
| Molecular weight | 17-25 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Please store the whole kit at -20°C upon receipt ,and protect from light. The kit is valid for 17 months. Please refer to the table below Materials supplied and Storage conditions to store all the components. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Interleukin 38 (IL-38) is a 16.87 kDa cytokine with 152 amino acid residues and a member of the interleukin-1 (IL-1) family. IL-38 is primarily secreted from basal epithelia of the skin and B cells of the tonsil, spleen, and thymus. It plays essential roles in inflammation and host defense by mediating NF-κB, AP1, and JNK signaling pathways when IL-38 binds to the receptors like IL1RAPL1 and IL-36R. In addition, IL-38 participates in down-regulating cell proliferation, migration, and up-regulating IL-6 and IL-10. |
| Alternative | interleukin 1 family, member 10, IL1F10 |
| Accession | Q8R459 |
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