| Product name | Mouse IGF-II Protein, His tag (Animal-Free) |
| Sequence | Amino acid sequence derived from Mouse IGF-II Protein (Ala25-Glu91) (P09535) was expressed with 6×His tag at the N-terminus |
| Applications | His tag |
| Applications notes | Mouse |
| Activity | Measured by its ability to induce MCF-7 cells proliferation.The ED50 for this effect is <6 ng/mL |
| Protein length | The recombinant Mouse IGF-II Protein consists of 67 amino acids and predicts a molecular mass of 8.20 kDa |
| Preparation method | E. coli |
| Purity | >98% as determined by SDS-PAGE. |
| Alternative | AL033362, Igf-2, M6pr, Mpr, Peg, Peg2 |
| Formulation | Lyophilized from PBS, pH 8.0 |
| Features & Benefits | Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method. |
| Molecular weight | 8.20 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously |
| Storage instructions | Please store the whole kit at -20°C upon receipt ,and protect from light. The kit is valid for 24 months. Please refer to the table below Materials supplied and Storage conditions to store all the components. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Mouse Insulin Like Growth Factors 2 (IGF-II) is a member of the Insulin-like Growth Factors. IGF-II is mainly expressed from early embryonic somatic tissues, liver, and epithelial cells lining the surface of the brain. IGF-II is mediating the embryonic development and placental growth, while also promoting tumor growth. IGF-II affects regulation of cell proliferation, growth, migration, differentiation and survival via binding to IGF-I receptor. |
| Alternative | AL033362, Igf-2, M6pr, Mpr, Peg, Peg2 |
| Accession | P09535 |
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