| Product name | MACC1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human MACC1 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 97kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al. 2009 [PubMed: 19098908]). |
| Gene ID | 346389 |
| Alternative | MACC1; Metastasis-associated in colon cancer protein 1; SH3 domain-containing protein 7a5 |
| Others | MACC1 Polyclonal Antibody detects endogenous levels of MACC1 protein. |
| Accession | Q6ZN28 |
| Observed Band(KD) | 97 |
Fig. Western Blot analysis of L929 cells using MACC1 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
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