| Product name | M3K14 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human M3K14 protein at amino acid sequence of 90-170 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 104kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14) encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. MAP3K14 is a Protein Coding gene. Diseases associated with MAP3K14 include Nik Deficiency. Among its related pathways are 4-1BB Pathway and RANK Signaling in Osteoclasts. |
| Gene ID | 9020 |
| Alternative | Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK |
| Others | The antibody detects endogenous levels of M3K14 protein |
| Accession | Q99558 |
| Observed Band(KD) | 104 |
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