| Product name | LRRK2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human LRRK2 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | IHC,IF |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 277kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. Leucine Rich Repeat Kinase 2 is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. |
| Gene ID | 120892 |
| Alternative | Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin |
| Others | The antibody detects endogenous levels of LRRK2 protein |
| Accession | Q5S007 |
| Observed Band(KD) | 277 |
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