| Product name | LARP1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human LARP1 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | La-related protein 1; La ribonucleoprotein domain family member 1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 120kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | LARP1 (La Ribonucleoprotein Domain Family Member 1) is a Protein Coding gene. Among its related pathways are Translational Control. RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex Associates with the mRNA 5cap in an MTOR-dependent manner and associates with mRNAs containing a 5 terminal oligopyrimidine (5TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5TOP, thereby regulating cell growth and proliferation Positively regulates the replication of dengue virus |
| Gene ID | 23367 |
| Alternative | La-related protein 1; La ribonucleoprotein domain family member 1 |
| Others | The antibody detects endogenous levels of LARP1 protein |
| Accession | Q6PKG0 |
| Observed Band(KD) | 120 |
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