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KLK5 Polyclonal Antibody

KLK5 Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP59064)
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Specification

Product name KLK5 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human KLK5 protein
Host Rabbit
Reactivity Human
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Kallikrein-5; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 32kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. Kallikrein Related Peptidase 5 is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID 25818
Alternative Kallikrein-5; Kallikrein-like protein 2; KLK-L2; Stratum corneum tryptic enzyme
Others The antibody detects endogenous levels of KLK5 protein
Accession Q9Y337
Observed Band(KD) 32

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