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KCNA6 Polyclonal Antibody

KCNA6 Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP59012)
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Specification

Product name KCNA6 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human KCNA6 protein at amino acid sequence of 420-500
Host Rabbit
Reactivity Human,Rat,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel HBK2; Voltage-gated potassium channel subunit Kv1.6

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 58kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCNA6 (Potassium Voltage-Gated Channel Subfamily A Member 6) encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12.
Gene ID 3742
Alternative Potassium voltage-gated channel subfamily A member 6; Voltage-gated potassium channel HBK2; Voltage-gated potassium channel subunit Kv1.6
Others The antibody detects endogenous levels of KCNA6 protein
Accession P17658
Observed Band(KD) 58

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