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KAISO Polyclonal Antibody

KAISO Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP59002)
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Specification

Product name KAISO Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human KAISO protein at amino acid sequence of 100-180
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Transcriptional regulator Kaiso Zinc finger and BTB domain-containing protein 33

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 73kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background ZBTB33 (Zinc Finger And BTB Domain Containing 33) encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. ZBTB33 is a Protein Coding gene. Diseases associated with ZBTB33 include Epithelial Malignant Thymoma and Dendritic Cell Thymoma. Among its related pathways are Wnt Signaling Pathway and Pluripotency.
Gene ID 10009
Alternative Transcriptional regulator Kaiso Zinc finger and BTB domain-containing protein 33
Others The antibody detects endogenous levels of KAISO protein
Accession Q86T24
Observed Band(KD) 73

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