| Product name | JAK1 Mouse Monoclonal Antibody (7G6) |
| Immunogen | Synthetic Peptide of JAK1 at AA range of 960-1040 |
| Host | Mouse |
| Reactivity | Human,Rat,Mouse |
| Applications | IHC,IF |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-200;IF 1:50-200 |
| Clonality | Monoclonal |
| Preparation method | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Alternative | JAK1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 130kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | JAK1 (Janus kinase 1) encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. |
| Gene ID | 3716 |
| Alternative | JAK1 |
| Others | JAK1 protein detects endogenous levels of JAK1. |
| Accession | P23458 |
| Observed Band(KD) | 130 |
Fig.1. Immunohistochemical analysis of paraffin-embedded Human Lung Carcinoma Tissue using JAK1 Mouse mAb diluted at 1:200.
Fig.2. Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using JAK1 Mouse mAb diluted at 1:200.
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