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Integrin α1 Polyclonal Antibody

Integrin α1 Polyclonal Antibody

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Specification

Product name Integrin α1 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human Integrin α1 protein at amino acid sequence of 920-980
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications IHC,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Integrin alpha-1; CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1; CD antigen CD49a

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Integrin α1 encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
Gene ID 3672
Alternative Integrin alpha-1; CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1; CD antigen CD49a
Others The antibody detects endogenous levels of Integrin α1
Accession P56199

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-colon-cancer, antibody was diluted at 1:200.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200.

Fig.5. Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200.

Fig.5. Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200.

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