| Product name | INSI2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human INSI2 protein at amino acid sequence of 40-120 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Insulin-induced gene 2 protein; INSIG-2 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 24kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | INSIG2 (Insulin Induced Gene 2) is a Protein Coding gene. Among its related pathways are Metabolism and Sterol Regulatory Element-Binding Proteins (SREBP) signalling. The protein encoded by INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. |
| Gene ID | 51141 |
| Alternative | Insulin-induced gene 2 protein; INSIG-2 |
| Others | The antibody detects endogenous levels of INSI2 protein |
| Accession | Q9Y5U4 |
| Observed Band(KD) | 24 |
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