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IL16 Polyclonal Antibody

IL16 Polyclonal Antibody

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Specification

Product name IL16 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human IL16 protein at amino acid sequence of 900-960
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:10000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Pro-interleukin-16; Pro-IL16; Pro-IL16;

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 67kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. IL16 (Interleukin 16) is a Protein Coding gene. Diseases associated with IL16 include Whipple Disease and Viral Meningitis. Among its related pathways are Akt Signaling and PEDF Induced Signaling.
Gene ID 3603
Alternative Pro-interleukin-16; Pro-IL16; Pro-IL16;
Others The antibody detects endogenous levels of IL16
Accession Q14005
Observed Band(KD) 67

Image & description

Fig.1. Western blot analysis of MCF7 SW480 Mouse-LIVER Mouse-lung Mouse-KIDNEY lysate, antibody was diluted at 1:500. HRP, Goat Anti-Rabbit IgG (Cat #: A21020) secondary antibody was diluted at 1:20000.

Fig.1. Western blot analysis of MCF7 SW480 Mouse-LIVER Mouse-lung Mouse-KIDNEY lysate, antibody was diluted at 1:500. HRP, Goat Anti-Rabbit IgG (Cat #: A21020) secondary antibody was diluted at 1:20000.

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