| Product name | IL-16 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human IL-16 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | IL16; Pro-interleukin-16 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 140kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Pro-interleukin-16 encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants. |
| Gene ID | 3603 |
| Alternative | IL16; Pro-interleukin-16 |
| Others | IL-16 Polyclonal Antibody detects endogenous levels of IL-16 protein. |
| Accession | Q14005 |
| Observed Band(KD) | 140 |
Fig.1. Western Blot analysis of 293, HepG2, BXPC-3, Raji, Mouse lung, Mouse brain, Mouse spleen cells using IL-16 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100.
Fig.3. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100.
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