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IL-13Rα1 (phospho Tyr405) Polyclonal Antibody

IL-13Rα1 (phospho Tyr405) Polyclonal Antibody

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Specification

Product name IL-13Rα1 (phospho Tyr405) Polyclonal Antibody
Immunogen Synthesized peptide derived from human IL-13Rα1 around the phosphorylation site of Y405
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative IL13RA1; IL13R; IL13RA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 49kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by IL13RA1 is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Gene ID 3597
Alternative IL13RA1; IL13R; IL13RA; Interleukin-13 receptor subunit alpha-1; IL-13 receptor subunit alpha-1; IL-13R subunit alpha-1; IL-13R-alpha-1; IL-13RA1; Cancer/testis antigen 19; CT19; CD antigen CD213a1
Others Phospho-IL-13Rα1 (Y405) Polyclonal Antibody detects endogenous levels of IL-13Rα1 protein only when phosphorylated at Y405.
Accession P78552
Observed Band(KD) 49

Image & description

Fig. Western Blot analysis of 3T3 cells using Phospho-IL-13Rα1 (Y405) Polyclonal Antibody.

Fig. Western Blot analysis of 3T3 cells using Phospho-IL-13Rα1 (Y405) Polyclonal Antibody.

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