| Product name | IGF2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human IGF2 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat,Pig |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Insulin-like growth factor II; IGF-II; Somatomedin-A; T3M-11-derived growth factor |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 10kD or 19kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | IGF2 encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. IGF2 (Insulin Like Growth Factor 2) is a Protein Coding gene. Diseases associated with IGF2 include Growth Restriction, Severe, With Distinctive Facies and Silver-Russell Syndrome. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and p70S6K Signaling. |
| Gene ID | 3481 |
| Alternative | Insulin-like growth factor II; IGF-II; Somatomedin-A; T3M-11-derived growth factor |
| Others | The antibody detects endogenous levels of IGF2 protein |
| Accession | P01344 |
| Observed Band(KD) | 19 |
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