| Product name | Human M-CSF Protein |
| Sequence | Amino acid sequence derived from Human M-CSF (Glu33-Ser190) (P09603-3) was expressed. |
| Applications | No tag |
| Applications notes | Human |
| Activity | Measured by its ability to induce proliferation in M-NFS-60 cells. The ED50 for this effect is 0.7344 ng/mL. |
| Protein length | The recombinant Human M-CSF consists of 158 amino acids and predicts a molecular mass of 19 kDa. |
| Preparation method | E.coli |
| Purity | > 95% as determined by SDS-PAGE |
| Molecular Formula | 19 kDa |
| Alternative | Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; MCSF; Lanimostim; CSF1 |
| Formulation | Lyophilized from sterile 20 mM Tris-HCl, 150mM NaCl, pH8.0. |
| Features & Benefits | Endotoxin :< 1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 19 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously |
| Storage instructions | Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness and fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis |
| Gene ID | 1435 |
| Alternative | Macrophage Colony-Stimulating Factor 1; CSF-1; M-CSF; MCSF; Lanimostim; CSF1 |
| Accession | P09603-3 |
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