| Product name | Human IL17F protein, His tag |
| Sequence | Amino acid sequence derived from Human IL17F (Q96PD4) (Arg31-Gln163) was expressed with 6×His tag at N-terminus. |
| Applications | His tag |
| Applications notes | Human |
| Activity | Testing in progress |
| Protein length | The recombinant Human IL17F consists of 133 amino acids and predicts a molecular mass of 14.9 kDa. |
| Preparation method | E.coli |
| Purity | > 95% as determined by SDS-PAGE |
| Molecular Formula | 14.9 kDa |
| Alternative | Interleukin-17F; IL-17F; Cytokine ML-1; IL17F |
| Formulation | Liquid in from sterile 20 mM PBS , 5% glycerol, pH 5.0 |
| Features & Benefits | Endotoxin :< 0.1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 14.9 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously |
| Storage instructions | Lyophilized recombinant Human IL17F protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Interleukin-17F(IL-17F) is a cytokine with similar sequence to IL-17.The most significant role of IL-17 is to participate in inducing and mediating pro-inflammatory reaction.IL-17 is usually associated with allergic reactions. IL-17F is expressed by activated T cells and only in activated CD4+ T cells and activated monocytes. IL-17F has been shown to stimulate the production of several other cytokines, including IL-6 and IL-8. Today, IL-17 represents a family of structurally related cytokines, which share a highly conserved C- terminal region, but differ from each other in N- terminal region and different biological functions. Six known members of this family, IL-17A to IL-17F, are secreted as homodimer. IL-17F also regulates cartilage matrix renewal and inhibits angiogenesis |
| Gene ID | 112744 |
| Alternative | Interleukin-17F; IL-17F; Cytokine ML-1; IL17F |
| Accession | Q96PD4 |
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