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Human IL-38 Protein, His tag (Animal-Free)

Human IL-38 Protein, His tag (Animal-Free)

Views(268) Publications(0) Catalog no(PRP1919)
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Specification

Product name Human IL-38 Protein, His tag (Animal-Free)
Sequence Amino acid sequence derived from Human IL-38 (Met1-Trp152) (Q8WWZ1) was expressed with 6×His tag at the C-terminus
Applications His tag
Applications notes Human
Activity Testing in progress
Protein length The recombinant Human IL-38 consists of 152 amino acids and predicts a molecular mass of 17.8 kDa
Preparation method E. coli
Purity >98% as determined by SDS-PAGE.
Alternative interleukin 1 family member 10, IL1F10, FIL1-theta, FKSG75, IL-1HY2, IL1-theta, IL1HY2

Product Properties

Formulation Lyophilized from PBS, pH 7.4
Features & Benefits Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.
Molecular weight 17.8 kDa
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously
Storage instructions Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA , 10%FBS or 0.1%BSA). Please prevent freeze-thaw cycles
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Interleukin-38 (IL-38) is a member of the interleukin-1 cytokine family. IL-38 is a ligand for soluble IL-1 receptor type I (IL-1RI). IL-38 could block the IL-36 pathway by inhibiting the IL-36 cytokine binding to their receptor. This process shows that IL-38 has anti-inflammatory properties. IL-38 is expressed in the immune organs, specifically in the skin and the tonsil, indispensable for B cell proliferation.
Alternative interleukin 1 family member 10, IL1F10, FIL1-theta, FKSG75, IL-1HY2, IL1-theta, IL1HY2
Accession Q8WWZ1

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