| Product name | Human IL-36β Protein |
| Sequence | Amino acid sequence derived from Human IL36 (Arg5-Glu164)(Q9NZH7)was expressed. |
| Applications | No tag |
| Applications notes | Human |
| Activity | Testing in progress |
| Protein length | The recombinant Human IL-36 beta consists of 160 amino acids and predicts a molecular mass of 17.37KDa |
| Preparation method | E.coli |
| Purity | > 98 % as determined by SDS-PAGE |
| Molecular Formula | 17.37 KDa |
| Alternative | Il36b,Fil1e,Il1f8,Interleukin-36 beta,Interleukin-1 family member 8,IL-1F8 |
| Formulation | Lyophilized from sterile 20mM Tris，0.15M NaCl, pH 7.4. |
| Features & Benefits | < 0.1 EU per μg of the protein as determined by the LAL method. |
| Molecular weight | 17.37 KDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage instructions | Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Interleukin-36 beta (IL-36β) is an 18 kDa cytokine with 154 amino acid residues. IL-36β, the ligand of IL-36R, is expressed in keratinocytes and plays a significant role in inflammatory responses. IL-36β regulates biological functions like the differentiation of T cells. Moreover, IL-36β recruits neutrophils via inducing the expression of cytokines and chemokines, such as IL-17C, granulocyte colony-stimulating factor (G-CSF), IL-8, CXCL-1, and tumor necrosis factor (TNF). |
| Gene ID | 27177 |
| Alternative | Il36b,Fil1e,Il1f8,Interleukin-36 beta,Interleukin-1 family member 8,IL-1F8 |
| Accession | Q9NZH7-2 |
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