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Human IL-19 Protein, His tag (Animal-Free)

Human IL-19 Protein, His tag (Animal-Free)

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Specification

Product name Human IL-19 Protein, His tag (Animal-Free)
Sequence Amino acid sequence derived from Human IL-19 (Leu63-ALa215) (Q9UHD0) was expressed with 6×His tag at the C-terminus
Applications His tag
Applications notes Human
Activity Measured by its ability to induce proliferation in BaF3 cells transfected with human IL-20 R alpha and human IL-20 R beta. The ED50 for this effect is <1.2 ng/mL
Protein length The recombinant Human IL-19 consists of 153 amino acids and predicts a molecular mass of 18.69 kDa
Preparation method E. coli
Purity >98% as determined by SDS-PAGE.
Alternative Melanoma differentiation-associated protein-like protein

Product Properties

Formulation Lyophilized from PBS, pH 8.0
Features & Benefits Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.
Molecular weight 18.69 kDa
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously
Storage instructions Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA , 10%FBS or 0.1%BSA). Please prevent freeze-thaw cycles
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Interleukin 19 (IL-19) is a type of anti-inflammatory cytokine. It promotes the Th2 T-cell response which supports an anti-inflammatory lymphocyte phenotype, dampens the Th1 T-cell response and IFNγ secretion, increases IL-10 expression in peripheral blood mononuclear cells, and inhibits the production of IgG from B cells
Alternative Melanoma differentiation-associated protein-like protein
Accession Q9UHD0

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