Product name | Human Galectin-3 Protein, His tag (Animal-Free) |
Sequence | Amino acid sequence derived from human Galectin-3 (Ala2-Ile250). |
Protein length | 32 kDa |
Preparation method | E. coli |
Purity | >95% as determined by SDS-PAGE. |
Alternative | IgE-binding protein, MAC2, L-29, CPB-35 |
Features & Benefits | Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method. |
Molecular weight | 32 kDa |
Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
Storage instructions | Please store the whole kit at 4°C upon receipt ,and protect from light. The kit is valid for 37 months. Please refer to the table below Materials supplied and Storage conditions to store all the components. |
Shipping | Gel pack with blue ice. |
Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
Background | Galectin-3 (Gal-3) is one of the lectin family members, which is the only chimera‑type galectin, containing one carbohydrate recognition domain (CRD) connected to a long, flexible N‑terminal domain. The C‑terminal CRD is responsible for β-galactoside binding, and the N‑terminal domain is essential for its multimerization, and interaction with other intracellular proteins. Galectin-3 is predominantly presented in the cytoplasm and expressed on the cell surface, and then often secreted into biological fluids, such as serum and urine. Numerous studies have indicated that galectin-3 plays a crucial role in cell proliferation, apoptosis, gene expression, immune surveillance, inflammation, fibrosis, and host defense. |
Alternative | IgE-binding protein, MAC2, L-29, CPB-35 |
Accession | P17931 |
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