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Human FGF16 Protein

Human FGF16 Protein

Views(302) Publications(0) Catalog no(PRP1082)
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Specification

Product name Human FGF16 Protein
Sequence Amino acid sequence derived from Human FGF16(Ala2-Arg207)(O43320)was expressed.
Applications No tag
Applications notes Human
Activity Measured by its ability to induce proliferation in Balb/3T3 cells. The ED50 for this effect is 5.997 ng/mL.
Protein length The recombinant Human FGF16 consists of 206 amino acids and predicts a molecular mass of 23.6 kDa.
Preparation method E. coli
Purity > 98 % as determined by SDS-PAGE
Alternative FGF16; Fibroblast Growth Factor 16;Metacarpal 4-5 Fusion; FGF-16;MF4

Product Properties

Formulation Lyophilized from 20 mM Tris-HCl, 500 mM NaCl, pH8.0
Features & Benefits Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.
Molecular weight 23.6 kDa
Usage notes Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously.
Storage instructions Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA , 10%FBS or 0.1%BSA). Please prevent freeze-thaw cycles
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background FGF16 is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the MEF2 site resulted in a blunting of FGF16 promoter activity in transfected neonatal rat cardiac myocytes, that chromatin remodeling and MEF2 binding in the FGF16 promoter contribute to expression in the postnatal heart.
Gene ID 8823
Alternative FGF16; Fibroblast Growth Factor 16;Metacarpal 4-5 Fusion; FGF-16;MF4
Accession O43320

Image & description

Fig.SDS-PAGE analysis of Human FGF16 Protein

Fig.SDS-PAGE analysis of Human FGF16 Protein

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