| Product name | Human BMP-9 Protein, His tag (Animal-Free) |
| Sequence | Amino acid sequence derived from Human BMP-9 (Ser320-Arg429) (Q9UK05) was expressed with 6×His tag at the N-terminus. |
| Applications | His tag |
| Applications notes | Human |
| Activity | Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED₅₀ for this effect is <0.4 ng/mL. |
| Protein length | The recombinant Human BMP-9 consists of 110 amino acids and predicts a molecular mass of 12.89 kDa. |
| Preparation method | E.coli |
| Purity | > 98 % as determined by SDS-PAGE |
| Molecular Formula | 12.89 kDa |
| Alternative | bone morphogenetic protein 9, NAP-1, BMP9 |
| Formulation | Lyophilized from sterile 20mM sodium citrate,0.2 M NaCl, pH 3.5. |
| Features & Benefits | Endotoxin :< 0.01 EU per 1 μg of the protein as determined by the LAL method. |
| Molecular weight | 12.89 kDa |
| Usage notes | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously. |
| Storage instructions | Lyophilized protein product should be stored desiccated below -18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (5% HSA,10% FBS or 0.1%BSA). Please prevent freeze-thaw cycles. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Human bone morphogenetic protein 9 (BMP-9), also known as growth differentiation factor 2 (GDF-2), is a transforming growth factor β A member of the BMP subgroup of the superfamily protein, which transmits signals through heterodimeric complexes composed of type I and type II BMP receptors. BMP-9 regulates the development and function of various embryonic and adult tissues. BMP-9 is synthesized and secreted by non parenchymal cells in the liver, which can promote lipid metabolism and inhibit glucose production. BMP-9 plays an important role in the development and maintenance of cholinergic neuron phenotype in the embryonic central nervous system. BMP-9 also induces mesenchymal stem cells to differentiate into chondrocyte lines. At low concentrations, BMP-9 is a proliferation factor of hematopoietic progenitor cells; but at high concentrations, it will promote TGF- β The production of 1 inhibits the formation of blood progenitor cell colonies |
| Gene ID | 2658 |
| Alternative | bone morphogenetic protein 9, NAP-1, BMP9 |
| Accession | Q9UK05 |
You must be logged in to post a review.
Reviews
There are no reviews yet.