| Product name | Hrs (phospho Tyr216) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human Hrs around the phosphorylation site of Y216 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | HGS; HRS; Hepatocyte growth factor-regulated tyrosine kinase substrate; Hrs; Protein pp110 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 115kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Hepatocyte growth factor-regulated tyrosine kinase substrate encoded by HGS regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. Hepatocyte growth factor-regulated tyrosine kinase substrate sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation. |
| Gene ID | 9146 |
| Alternative | HGS; HRS; Hepatocyte growth factor-regulated tyrosine kinase substrate; Hrs; Protein pp110 |
| Others | Phospho-Hrs (Y216) Polyclonal Antibody detects endogenous levels of Hrs protein only when phosphorylated at Y216. |
| Accession | O14964 |
| Observed Band(KD) | 115 |
Fig. Western Blot analysis of various cells using Phospho-Hrs (Y216) Polyclonal Antibody.
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