| Product name | Histone deacetylase 1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Histone deacetylase 1 at AA range: 410-490 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | HDAC1; RPD3L1; Histone deacetylase 1; HD1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 55kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone deacetylase 1 encoded by HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. |
| Gene ID | 3065 |
| Alternative | HDAC1; RPD3L1; Histone deacetylase 1; HD1 |
| Others | Histone deacetylase 1 Polyclonal Antibody detects endogenous levels of Histone deacetylase 1 protein. |
| Accession | Q13547 |
| Observed Band(KD) | 55 |
Fig.1. Western Blot analysis of various cells using Histone deacetylase 1 Polyclonal Antibody diluted at 1:1000.
Fig.2. Western Blot analysis of hela cells using Histone deacetylase 1 Polyclonal Antibody diluted at 1:1000.
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