| Product name | Histamine H3 Receptor Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human Histamine H3 Receptor at AA rangle: 260-340 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | HRH3; GPCR97; Histamine H3 receptor; H3R; HH3R; G-protein coupled receptor 97 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 49kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. HRH3 encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. |
| Gene ID | 11255 |
| Alternative | HRH3; GPCR97; Histamine H3 receptor; H3R; HH3R; G-protein coupled receptor 97 |
| Others | Histamine H3 Receptor Polyclonal Antibody detects endogenous levels of Histamine H3 Receptor protein. |
| Accession | Q9Y5N1 |
| Observed Band(KD) | 49 |
Fig. Western Blot analysis of COLO205 cells using Histamine H3 Receptor Polyclonal Antibody.
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