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HES5 Polyclonal Antibody

HES5 Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP58774)
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Specification

Product name HES5 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human HES5 protein at amino acid sequence of 10-90
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Transcription factor HES-5; Class B basic helix-loop-helix protein 38; bHLHb38; Hairy and enhancer of split 5

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 18kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background HES5 (Hes Family BHLH Transcription Factor 5) encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of HES5, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of HES5 have been associated with developmental diseases and cancer. HES5 is a Protein Coding gene. Diseases associated with HES5 include Valproate Embryopathy, Susceptibility To. Among its related pathways are Signaling by NOTCH1 and NOTCH2 Activation and Transmission of Signal to the Nucleus.
Gene ID 388585
Alternative Transcription factor HES-5; Class B basic helix-loop-helix protein 38; bHLHb38; Hairy and enhancer of split 5
Others The antibody detects endogenous levels of HES5 protein
Accession Q5TA89
Observed Band(KD) 18

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