| Product name | GSK3α/β Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human GSK3α/β around the non-phosphorylation site of Y279/216 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat,Drosophila,Drosophila |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 51,46kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | GSK3A encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. Glycogen synthase kinase-3 alpha also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. |
| Gene ID | 2931 |
| Alternative | GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B |
| Others | GSK3α/β Polyclonal Antibody detects endogenous levels of GSK3α/β protein. |
| Accession | P49840/P49841 |
| Observed Band(KD) | 51,46 |
Fig.1. Western Blot analysis of various cells using GSK3α/β Polyclonal Antibody diluted at 1:1000.
Fig.2. Western Blot analysis of 293 cells using GSK3α/β Polyclonal Antibody diluted at 1:1000.
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