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GSC2 Polyclonal Antibody

GSC2 Polyclonal Antibody

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Specification

Product name GSC2 Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human GSC2 at AA range: 100-180
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative GSC2; GSCL; Homeobox protein goosecoid-2; GSC-2; Homeobox protein goosecoid-like; GSC-L

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 25kD
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. GSC2 is expressed in a limited number of adult tissues, as well as in early human development.
Gene ID 2928
Alternative GSC2; GSCL; Homeobox protein goosecoid-2; GSC-2; Homeobox protein goosecoid-like; GSC-L
Others GSC2 Polyclonal Antibody detects endogenous levels of GSC2 protein.
Accession O15499
Observed Band(KD) 25

Image & description

Fig. Western Blot analysis of various cells using GSC2 Polyclonal Antibody diluted at 1:1000.

Fig. Western Blot analysis of various cells using GSC2 Polyclonal Antibody diluted at 1:1000.

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