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GPIX Polyclonal Antibody

GPIX Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP58683)
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Specification

Product name GPIX Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human GPIX protein at amino acid sequence of Internal
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Platelet glycoprotein IX; GP-IX; GPIX; Glycoprotein 9; CD_antigen: CD42a

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 19kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GP9 encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
Gene ID 2815
Alternative Platelet glycoprotein IX; GP-IX; GPIX; Glycoprotein 9; CD_antigen: CD42a
Others The antibody detects endogenous levels of GPIX protein
Accession P14770
Observed Band(KD) 19

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