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GNLY Polyclonal Antibody

GNLY Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP58659)
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Specification

Product name GNLY Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human GNLY protein
Host Rabbit
Reactivity Human
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Granulysin; Lymphokine LAG-2; Protein NKG5; T-cell activation protein 519

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 15kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The product of GNLY is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID 10578
Alternative Granulysin; Lymphokine LAG-2; Protein NKG5; T-cell activation protein 519
Others The antibody detects endogenous levels of GNLY protein
Accession P22749
Observed Band(KD) 15

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