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GH Polyclonal Antibody

GH Polyclonal Antibody

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Specification

Product name GH Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human GH protein at amino acid sequence of 180-217
Host Rabbit
Reactivity Human,Rat,Mouse,
Applications IHC,IF,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone Growth hormone variant; GH-V; Growth hormone 2; Placenta-specific growth hormone

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The Growth Hormone 1 encoded by GH1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. GH1, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Gene ID 2688
Alternative Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone Growth hormone variant; GH-V; Growth hormone 2; Placenta-specific growth hormone
Others The antibody detects endogenous levels of GH
Accession P01241/P01242

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-placenta, antibody was diluted at 1:200.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

Fig.3. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

Fig.4. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

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