| Product name | GEMI8 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human GEMI8 protein at amino acid sequence of 180-260 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Gem-associated protein 8; Gemin-8; Protein FAM51A1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 26kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | GEMIN8 (Gem Nuclear Organelle Associated Protein 8) is a Protein Coding gene. Among its related pathways are Transport of the SLBP independent Mature mRNA and Gene Expression. The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for GEMIN8. |
| Gene ID | 54960 |
| Alternative | Gem-associated protein 8; Gemin-8; Protein FAM51A1 |
| Others | The antibody detects endogenous levels of GEMI8 protein |
| Accession | Q9NWZ8 |
| Observed Band(KD) | 26 |
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