| Product name | FYCO1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human FYCO1 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | FYVE and coiled-coil domain-containing protein 1; Zinc finger FYVE domain-containing protein 7 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 162kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | FYCO1 encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in FYCO1 are a cause of autosomal recessive congenital cataract-2 (CATC2). FYCO1 (FYVE And Coiled-Coil Domain Containing 1) is a Protein Coding gene. Diseases associated with FYCO1 include Cataract 18, Autosomal Recessive and Early-Onset Nuclear Cataract. |
| Gene ID | 79443 |
| Alternative | FYVE and coiled-coil domain-containing protein 1; Zinc finger FYVE domain-containing protein 7 |
| Others | The antibody detects endogenous levels of FYCO1 protein |
| Accession | Q9BQS8 |
| Observed Band(KD) | 162 |
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