| Product name | FHR1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human FHR1 protein |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Complement factor H-related protein 1; FHR-1; H factor-like protein 1; H-factor-like 1; H36 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 36kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | CFHR1 encodes Complement Factor H Related 1 belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. |
| Gene ID | 3078 |
| Alternative | Complement factor H-related protein 1; FHR-1; H factor-like protein 1; H-factor-like 1; H36 |
| Others | The antibody detects endogenous levels of FHR1 protein |
| Accession | Q03591 |
| Observed Band(KD) | 36 |
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