| Product name | EYA1/EYA4 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human EYA1/EYA4 protein at amino acid sequence of 271-320 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Eyes absent homolog 1; EYA1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | EYA1 encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of EYA1 have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Alternatively spliced transcript variants have been identified for this gene EYA1 (EYA Transcriptional Coactivator And Phosphatase 1) is a Protein Coding gene. Diseases associated with EYA1 include Otofaciocervical Syndrome and Branchiootic Syndrome 1. Among its related pathways are DNA Double Strand Break Response and DNA Double-Strand Break Repair. |
| Gene ID | 2138/2140 |
| Alternative | Eyes absent homolog 1; EYA1 |
| Others | The antibody detects endogenous levels of EYA1/EYA4 |
| Accession | Q99502/O95677 |
Fig.1. Immunohistochemical analysis of paraffin-embedded Human-kidney, antibody was diluted at 1:100.
Fig.2. Immunohistochemical analysis of paraffin-embedded Human-kidney, antibody was diluted at 1:100.
Fig.3. Immunohistochemical analysis of paraffin-embedded Human-brain, antibody was diluted at 1:100.
Fig.4. Immunohistochemical analysis of paraffin-embedded Human-brain, antibody was diluted at 1:100.
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