| Product name | EphA2 (phospho Tyr588) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human EphA2 around the phosphorylation site of Y588 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | EPHA2; ECK; Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 130kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | EPHA2 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA2 encodes EPH receptor A2 that binds ephrin-A ligands. Mutations in EPHA2 are the cause of certain genetically-related cataract disorders. |
| Gene ID | 1969 |
| Alternative | EPHA2; ECK; Ephrin type-A receptor 2; Epithelial cell kinase; Tyrosine-protein kinase receptor ECK |
| Others | Phospho-EphA2 (Y588) Polyclonal Antibody detects endogenous levels of EphA2 protein only when phosphorylated at Y588. |
| Accession | P29317 |
| Observed Band(KD) | 130 |
Fig. Western Blot analysis of various cells using Phospho-EphA2 (Y588) Polyclonal Antibody.
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