| Product name | EDN2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human EDN2 protein |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Endothelin-2; ET-2; Preproendothelin-2; PPET2 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 19kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | EDN2 encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. Endothelin 2 is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. |
| Gene ID | 1907 |
| Alternative | Endothelin-2; ET-2; Preproendothelin-2; PPET2 |
| Others | The antibody detects endogenous levels of EDN2 protein |
| Accession | P20800 |
| Observed Band(KD) | 19 |
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