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DRAM1 Polyclonal Antibody

DRAM1 Polyclonal Antibody

Views(13) Publications(0) Catalog no(ABP58419)
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Specification

Product name DRAM1 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human DRAM1 protein at amino acid sequence of 151-200
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative DNA damage-regulated autophagy modulator protein 1; Damage-regulated autophagy modulator

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 26kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background DRAM1 is regulated as part of the p53 tumor suppressor pathway. DRAM1 encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of DRAM1 is associated with various tumors. This gene has a pseudogene on chromosome 4.
Gene ID 55332
Alternative DNA damage-regulated autophagy modulator protein 1; Damage-regulated autophagy modulator
Others The antibody detects endogenous levels of DRAM1 protein
Accession Q8N682
Observed Band(KD) 26

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