| Product name | DOC11 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human DOC11 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Dedicator of cytokinesis protein 11; Dedicator of cytokinesis protein 11; ACG; Zizimin-2 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 228kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | DOCK11 (Dedicator Of Cytokinesis 11) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and G-protein signaling_Regulation of CDC42 activity. Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42. |
| Gene ID | 139818 |
| Alternative | Dedicator of cytokinesis protein 11; Dedicator of cytokinesis protein 11; ACG; Zizimin-2 |
| Others | The antibody detects endogenous levels of DOC11 protein |
| Accession | Q5JSL3 |
| Observed Band(KD) | 228 |
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