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DICER Polyclonal Antibody

DICER Polyclonal Antibody

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Specification

Product name DICER Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human DICER protein
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Endoribonuclease Dicer; Helicase with RNase motif; Helicase MOI

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 211kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background DICER gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.
Gene ID 23405
Alternative Endoribonuclease Dicer; Helicase with RNase motif; Helicase MOI
Others The antibody detects endogenous levels of DICER protein
Accession Q9UPY3
Observed Band(KD) 211

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