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DEDD Polyclonal Antibody

DEDD Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP58349)
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Specification

Product name DEDD Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human DEDD protein at amino acid sequence of 90-170
Host Rabbit
Reactivity Human,Mouse,Rat
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Death effector domain-containing protein; DEDPro1; Death effector domain-containing testicular molecule; FLDED-1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 34kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
Gene ID 9191
Alternative Death effector domain-containing protein; DEDPro1; Death effector domain-containing testicular molecule; FLDED-1
Others The antibody detects endogenous levels of DEDD protein
Accession O75618
Observed Band(KD) 34

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