| Product name | D4DR Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the C-terminal region of human D4DR at AA range: 330-410 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | DRD4; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 48kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | DRD4 encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in DRD4 have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. DRD4 contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. |
| Gene ID | 1815 |
| Alternative | DRD4; D(4) dopamine receptor; D(2C) dopamine receptor; Dopamine D4 receptor |
| Others | D4DR Polyclonal Antibody detects endogenous levels of D4DR protein. |
| Accession | P21917 |
| Observed Band(KD) | 48 |
Fig.1. Western Blot analysis of various cells using D4DR Polyclonal Antibody.
Fig.2. Western Blot analysis of K562 cells using D4DR Polyclonal Antibody.
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