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CYTS Polyclonal Antibody

CYTS Polyclonal Antibody

Views(2) Publications(0) Catalog no(ABP58326)
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Specification

Product name CYTS Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human CYTS protein
Host Rabbit
Reactivity Human,Rat
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Cystatin-S; Cystatin-4; Cystatin-SA-III; Salivary acidic protein 1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 15kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. CST4 is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. Cystatin S is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.
Gene ID 1472
Alternative Cystatin-S; Cystatin-4; Cystatin-SA-III; Salivary acidic protein 1
Others The antibody detects endogenous levels of CYTS protein
Accession P01036
Observed Band(KD) 15

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