| Product name | Cytokeratin 13 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human Cytokeratin 13 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | KRT13; Keratin; type I cytoskeletal 13; Cytokeratin-13; CK-13; Keratin-13; K13 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 52kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Keratin 13 encoded by KRT13 is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of KRT13 results in multiple transcript variants; however, not all variants have been described. |
| Gene ID | 3860 |
| Alternative | KRT13; Keratin; type I cytoskeletal 13; Cytokeratin-13; CK-13; Keratin-13; K13 |
| Others | Cytokeratin 13 Polyclonal Antibody detects endogenous levels of Cytokeratin 13 protein. |
| Accession | P13646 |
| Observed Band(KD) | 52 |
Fig.1. Western Blot analysis of various cells using Cytokeratin 13 Polyclonal Antibody.
Fig.2. Western Blot analysis of HepG2 cells using Cytokeratin 13 Polyclonal Antibody.
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