| Product name | CYP1B1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human CYP1B1 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse, |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications. |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | CYP1B1; Cytochrome P450 1B1; CYPIB1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 60kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in CYP1B1 have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. |
| Gene ID | 1545 |
| Alternative | CYP1B1; Cytochrome P450 1B1; CYPIB1 |
| Others | CYP1B1 Polyclonal Antibody detects endogenous levels of CYP1B1 protein. |
| Accession | Q16678 |
| Observed Band(KD) | 60 |
Fig.1. Western Blot analysis of various cells using CYP1B1 Polyclonal Antibody.
Fig.2. Western Blot analysis of Jurkat cells using CYP1B1 Polyclonal Antibody.
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