| Product name | Cyclophilin B Monoclonal Antibody |
| Immunogen | Synthetic Peptide |
| Host | Mouse |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,IHC,IF |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000-2000;IHC 1:100-200;IF 1:50-200 |
| Clonality | Monoclonal |
| Preparation method | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Alternative | PPIB; CYPB; Peptidyl-prolyl cis-trans isomerase B; PPIase B; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 21kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by PPIB (peptidylprolyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. |
| Gene ID | 5479 |
| Alternative | PPIB; CYPB; Peptidyl-prolyl cis-trans isomerase B; PPIase B; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP |
| Accession | P23284 |
Fig.1. Western blot analysis of 1) Hela, 2) Jurkat, 3) 293T, 4) Rat Liver Tissue, 5) 3T3, 6) HepG2 with Cyclophilin B Mouse mAb diluted at 1:2000.
Fig.2. Immunohistochemical analysis of paraffin-embedded Human Heptacarcinoma using Cyclophilin BMouse mAb diluted at 1:200.
Fig.3. Immunohistochemical analysis of paraffin-embedded Human Pancreatic Carcinoma using Cyclophilin BMouse mAb diluted at 1:200.
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